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lpetrich
16 Mar 2009, 09:39 AM
Vitalism is the theory that living things are alive as a result of some "vital force", as opposed to their being that way being an emergent property of appropriately-arranged nonliving matter (mechanism).

Vitalism is an old and popular hypothesis, perhaps an almost universal hypothesis before modern times. "Soul" or "spirit" essentially meant "vital force" in many cases. The ancient Greek atomists, well-known for their philosophical materialism, believed that there are vital-force (soul) atoms as well as other kinds of atoms. Aristotle even went so far as to identify three kinds of vital force: the vegetable soul, the animal soul, and the rational soul. However, it is nowadays completely discredited in mainstream science, though it survives as the "theoretical justification" for various "alternative medical therapies". Yes, forces like "qi / chi" and "prana" are versions of "vital force".

It's hard for me to find any good histories of that subject online; the most I've found is Carbon Chemistry (http://www.3rd1000.com/history/carbon.htm). Some accounts treat Friedrich Wöhler's 1828 synthesis of urea from ammonium cyanate as a Great Turning Point. However, this feat was hardly noticed at the time, and was celebrated only long afterwards. But it was counterevidence against a common view at the time, notably advocated by chemist Jöns Jakob Berzelius, that many compounds, the "organic" ones, could only be made by living things (the others are "inorganic"). And I suspect that this experiment is remembered because it was followed by numerous other experiments that pointed in the same direction.

In 1845, one of Wöhler's students, Adolph Kolbe, succeeded in making acetic acid from inorganic compounds, and in the 1850's, Pierre Berthelot succeeded in synthesizing numerous organic compounds from incorganic precursors, including methyl alcohol, ethyl alcohol, methane, benzene, and acetylene.

But a vitalist could still claim that this is not really counterevidence, because these substances could be made by that "vital force", in addition to being makable in the lab.

One of the last reputable vitalists in mainstream biology was Hans Driesch, who in 1895 made an odd discovery: he could take a fertilized sea-urchin egg that had started dividing, split it in two, and watch the two halves develop into two complete sea urchins, instead of two halves of one sea urchin. He concluded from this that there was some "vital force" responsible for development. However, in their first few divisions, a sea-urchin embryo's cells are uncommitted to any particular fate; that commitment only happens later, and Driesch had proposed a sort of "vital force of the gaps".

But one of his contemporaries, Eduard Buchner, discovered in 1897 that yeast-cell contents could cause fermentation in the absence of whole yeast cells. He followed up in 1903 by making the first discovery of one of the enzymes responsible (zymase).

And over the twentieth century, molecular biologists continued onward, scoring triumph after triumph, while totally ignoring the vital-force hypothesis. They have finished what Wöhler started, mapping out numerous metabolic pathways, including biosynthesis ones. And they have solved several other biological riddles, like heredity. There are still some things that have resisted molecular biologists' efforts, like how one gets from genes to macroscopic shapes, but from what can be determined about that, a vital force is totally superfluous there also.

I finally note an odd circumstance: present-day vitalists are totally apolitical about their vitalism, in strong contrast with creationists, who are sometimes shamelessly political about their beliefs. There are not many vitalists who want equal time for chi and prana in molecular-biology classes. And molecular biologists devote next to no effort to debunking chi and prana.

Ray Moscow
16 Mar 2009, 09:46 AM
This is an interesting subject. I also read that vitalism had been "disproven" but really had never found where or how.

(I have a strong interest in "qi" theory because of my martial arts background, but I've never really found anything verifiable that can't be explained in some way by conventional physics.)

I think vitalism has mostly just been rendered superfluous by our increasing understanding of biology, biochemisty, molecular biology, etc.

lpetrich
14 Aug 2009, 07:53 PM
I've bumped this thread on account of rereading Vitalism, the article Vitalism (http://mechanism.ucsd.edu/~bill/teaching/philbio/vitalism.htm), from the Routledge Encyclopedia of Philosophy, and The Real Death of Vitalism: Implications of the Wöhler Myth (http://www.bioethicsjournal.com/past/cheng.html) (Anthony Cheng, Penn Bioethics Journal)

I was unable to find much insight on the fall of vitalism, though I found something on how the Wöhler-disproved-vitalism notion got started:
The Wöhler Myth, as historian of science Peter J. Ramberg calls it, originates from one account by Bernard Jaffe, the author of a popular history of chemistry in 1931 that is still in print today. “Ignoring all pretense of historical accuracy, Jaffe turned Wöhler into a crusader who made attempt after attempt to synthesize a natural product that would refute vitalism and lift the veil of ignorance, until ‘one afternoon the miracle happened’” (Ramberg, 2000, p. 170-195)
(Anthony Cheng, noting Ramberg, Peter J. (2000) The Death of Vitalism and the Birth of Organic Chemistry. Ambix, 47(3),170-195.)

I think that that's an entirely reasonable position. Wöhler's synthesis of urea was only one synthesis, and a biosynthesis vitalist could easily dismiss that as unimportant. But a biosynthesis vitalist would have a much harder time with Berthelot's work, because he made not one, but numerous organic compounds in his lab from non-biological starting materials. His performance had likely suggested that chemists' ability to make organic compounds is limited only by their skill and patience and other resources.

So instead of a sudden collapse, it was a slow death. But that is not nearly as dramatic as the Wöhler-disproved-vitalism version, it must be said. And it was not even vitalism as a whole, but a specific vitalist hypothesis; other vitalist ones could survive.

Berthold
15 Aug 2009, 07:40 AM
Don't forget Pasteur's role.

There was a political vitalist: Henri Bergson.

lpetrich
15 Aug 2009, 11:24 AM
Don't forget Pasteur's role.
I don't think that Pasteur had anything to do with it -- he did not work on metabolism or biochemistry, as far as I know.

There was a political vitalist: Henri Bergson.
How was he a political vitalist?

I like Bertrand Russell's evaluation of his work -- BR considered his vitalism poetic, rather than scientific.

Berthold
15 Aug 2009, 12:01 PM
Well, Pasteur worked on related things, such as optically active substances, and the debunking of spontaneous generation. I have, indeed, not found an explicit mentioning of vitalism in connection with him.

Bergson:
I remember seeing a documentary movie about WWI where elan vitale was mentioned as a popular term in connection with French patriotic endurance.
Otherwise, I now found that he worked in politics. From here (http://www.kirjasto.sci.fi/bergson.htm):
From 1914 until 1921 Édouard Le Roy functioned as Bergson's "permanent substitute" while the philosopher served on French diplomatic missions. Bergson resigned in 1921 in order to dedicate himself to his writing and to his work on behalf of the League of Nations. From 1921 to 1926 he acted as president of the committee on international cooperation of the League of Nations.
His political work may, of course, have been independent from his philosophy.

lpetrich
15 Aug 2009, 02:04 PM
Well, Pasteur worked on related things, such as optically active substances, and the debunking of spontaneous generation. I have, indeed, not found an explicit mentioning of vitalism in connection with him.
So he doesn't count.

Bergson:
I remember seeing a documentary movie about WWI where elan vitale was mentioned as a popular term in connection with French patriotic endurance.
Informal descriptions of being energetic != vitalism.

Otherwise, I now found that he worked in politics. ... His political work may, of course, have been independent from his philosophy.
I think that it was.


That aside, in 1912, biologist Jacques Loeb published a landmark work, The Mechanistic Conception of Life, available online at books.google.com (http://books.google.com/books?id=IVOPhYOmfBYC&dq=%22The+Mechanistic+Conception+of+Life%22&printsec=frontcover&source=bl&ots=XXxKTe5dv_&sig=a0bSjDLOSqZLraGrL78Z3GqOahE&hl=en&ei=XrSGSvCPOYagsgOz1PicBw&sa=X&oi=book_result&ct=result&resnum=5#v=onepage&q=&f=false), Questia, and perhaps other places. He described experiments on how, as Bertrand Russell put it, a sea urchin could have a pin for its father. He also offered this challenge:
... we must either succeed in producing living matter artificially, or we must find the reasons why this is impossible.
(pp. 5-6). It seems to me that he was challenging vitalists to show that vitalism is more than some theory of vital force of the gaps. In pp. 14-15, he took another swipe at vitalism:
It is, therefore, unwarranted to continue the statement that in addition to the acceleration of oxidations the beginning of individual life is determined by the entrance of a metaphysical "life principle" into the egg; and that death is determined, aside from the cessation of oxidations, by the departure of this "principle" from the body. In the case of the evaporation of water we are satisfied with the explanation given by the kinetic theory of gases and do not demand that to repeat a well-known jest of Huxley the disappearance of the "aquosity" be also taken into consideration.

He was referring to Thomas Henry Huxley's "aquosity" comments in The Physical Basis of Life (http://aleph0.clarku.edu/huxley/comm/PMG/PBofL.html) (1869).